Scaffold Proposal

The submission criteria of a proposed scaffold to be considered in CC4CARB are:

• Description of the scaffold, preferably a structure, and the goals/rationale for making a library.
• Rationale for why the scaffold represents a compelling hypothesis involving the treatment of Gram-negative or antibiotic resistant Gram-positive infections, plus references.
• Vision for testing scaffold analogs, including key microbes if known. Ability to test compounds not required but is highly preferred.
• Library design concepts are encouraged, but not necessary. Library design will be a collaborative effort between RTI and the external PI.
• Curriculum Vitae or NIH Biosketch.
• Innovation, novelty, and concepts addressing Gram-negative antimicrobial discovery and development will be prioritized if accepted.